Short Communication
Micronuclei and Other Nuclear Anomalies in Exfoliated Buccal and Uterine Cervical Cells of Healthy Armenian Women
Armen K. Nersesyan1,2, Nina S. Vartazaryan1, and Rouben M. Arutyunyan1
1 Department of Genetics and Cytology, State University, Yerevan, Armenia
2 Cancer Research Center, Yerevan, Armenia
Corresponding author: Armen K. Nersesyan, Ph.D. D.Sc
Department of Genetics and Cytology
State University
1 Alex Manoukian St
Yerevan 25, Armenia
Telephone: Tel: +3741 552352
Fax number: Fax: +3741 554641
E-mail address: armenn@freenet.am;
genetik@ysu.am
CEJOEM 2002, Vol.8. No.1.:39–43
Key words:
Micronuclei, nuclear anomalies, exfoliated cells
Abstract:
The levels of micronuclei (MN) and other nuclear anomalies (karyorrhexis, karyolysis, pycnosis,
binucleates, condensed chromatin, “broken egg”) were studied in exfoliated buccal and uterine
cervical cells of 10 postmenopausal and 10 healthy Armenian females with normal menstrual
function. The other nuclear anomalies were studied for the first time in cervical cells. In the MN
level, no significant difference was obtained between the two cell types or between the two
groups. However, the frequencies of cells displaying the other nuclear anomalies showed
significant difference in the cervical cells of postmenopausal females as compared to that of
women with regular menstrual function. The results suggest that the change might be attributed to
postmenopausal degenerative processes.
Received: 24 May 2002
Accepted: 01 July 2002
| Back |