Cytogenetic Monitoring of Radiological and Nuclear Worker

Doina C. Obreja1, Gabriella Bognár2, Katalin Szalma2, and György J. Köteles2

1 Institute of Public Health, Bucharest, Romania
2 “Frédéric Joliot-Curie” National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary

Corresponding author: Dr. Gabriella Bognár
    “Frédéric Joliot-Curie” National Research Institute for Radiobiology and Radiohygiene
    POB. 101
    H-1775 Budapest, Hungary
    Telephone: +36-1-482-2000/121
    E-mail: bognar@hp.osski.hu

CEJOEM 2007, Vol.13. No.1.: 17–24

Key words:
Lymphocyte, micronuclei, translocations, monitoring, radiological and nuclear workers

Abstract:
Micronucleus analysis and translocation detection by fluorescent in situ hybridization (FISH) technique in lymphocytes of radiological and nuclear workers were performed. None of the persons involved were exposed to over the occupational annual dose limits. Micronucleus frequencies tended to increase in function of cumulative exposure expressed by working years, though not overwhelming 40 per thousand cells, i.e. slightly more than the range of the occupationally not exposed population category. The translocation detection by FISH has not lead to detectable result for the persons cumulating 100–250 mSv during their working years.

Received: 15 February 2007
Accepted: 28 May 2007
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